BrachyClip Technology
A comprehensive solution for minimally invasive intra-operative permanent seed brachytherapy, specifically designed for open, laparoscopic, and robotic procedures.
ACCURATE
Precisely targeted radiation delivery to high-risk surgical margins
Optimized Dosimetry
Advanced planning ensures optimal dose distribution to tumor bed while minimizing exposure to healthy tissue
Predictable Outcomes
Consistent seed placement enables reproducible dosimetry calculations and treatment planning
Real-Time Verification
Radiopaque titanium markers allow for immediate imaging confirmation of placement

Clinical Impact
Accurate radiation delivery reduces the need for additional interventions and improves patient outcomes through targeted treatment of at-risk tissue.
Key Requirements for IPSB
"Prior techniques have been related to poor apposition of radioactive seeds. BrachyClip assures persistent placement and appropriate delivery of planned radiation."
Accurate seed placement
via any surgical approach
Secure fixation to ensure
efficacious dose distribution
Ability to precisely conform
IPSB to the residual margin
Minimal or no personnel
risk of radiation exposure
A Platform, Not Just a Product
BrachyClip's modular design enables continuous innovation and expansion beyond current brachytherapy applications
AI-Driven Imaging Tools
Integration with advanced imaging and artificial intelligence for real-time surgical margin assessment and treatment planning optimization.
Alternative Payloads
The BrachyClip delivery mechanism can accommodate various therapeutic payloads beyond traditional brachytherapy seeds.
Multi-Tumor Applications
Designed for adaptability across multiple solid tumor types, expanding addressable market opportunities.
Beyond Brachytherapy
While BrachyClip addresses an immediate clinical need in surgical margin management, its platform architecture positions the company for long-term growth through continuous innovation in targeted intra-operative therapeutics.
Monte Carlo Dosimetry Analysis
Advanced computational modeling validates BrachyClip's precise and uniform radiation dose distribution
Single Seed Dose Distribution

Relative dose distribution from a single BrachyClip seed showing concentrated, predictable radiation delivery
20-Seed Array Dose Distribution

Combined dose distribution from a 20-seed BrachyClip array demonstrating uniform coverage of the target area
Dose Uniformity — Above Clip (Y=+1cm)

Absorbed dose 1cm directly above the seed: 0.203 Rad/hr/mCi — demonstrating highly uniform dose delivery
Dose Uniformity — Below Clip (Y=-1cm)

Absorbed dose 1cm directly below the seed: 0.158 Rad/hr/mCi — confirming symmetric radiation penetration